Can Betal nut cause cancer??

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Can the consumption of betal nut cause cancer? :? OR any other health hazards?

Betal nut is widely consumed in the South Asian sub-continent, and is considered as an important cultural activity within this region.

If indeed, betal nut is hazardous to health, what would be the Islamic Ruling regarding consumption of Betal nut?
 
Constituents of betel nut are potentially carcinogenic. Long-term use has been associated with oral submucous fibrosis (OSF), pre-cancerous oral lesions (mouth wounds), and squamous cell carcinoma (cancer). Acute effects of betel chewing include worsening of asthma, low blood pressure, and rapid heart beat.

http://www.nlm.nih.gov/medlineplus/druginfo/natural/patient-betelnut.html
 

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