Question of the week

[جوري]

What is the diagnosis? typical presentation is an elderly male with lower back pain


this would be described by the pathologist as a perinuclear hoff

this one is on peripheral smear


would be described as rouleaux formation


and on x-ray


this would be described as punched out lytic lesion..
make the DX and tell me about the disease

thank you.. as usual 20pts rep points to first person who gets it correct =)

 

[Keltoi]

some form of cancer? I think lytic lesions are caused by a disease process like cancer.

 

[جوري]

yes yes you are hot.. but be more specific though ...
very good by the way...you are headed in the right direction...

 

[muzna]

i would say a bleeding disorder, say haemophilia..

 

[جوري]

well... in Hemophilia, you would be taking a blood test and coagulation factors but not a peripheral smear, or X-ray.. they would have more cartillage problems with blood spilling into the joints on minor trauma called hemarthrosis... but you wouldn't be getting the above findings... I have given really good clues by the way, and Keltoi was headed in the right direction... think more ca. than a bleeding disorder...
thank you by the way for participating

 

[muzna]

is it a myeloma?

 

[جوري]

kudos and reps for you.. it is Multiple myeloma, which is a cancer of the plasma cell....

 

[muzna]

that was hard..thanks..
keep the questions coming..i think i'm learning more med from sis ambrosia than from med school..